Jun Yoshioka Selected Research

Cardiomegaly (Heart Hypertrophy)

12/2007	Targeted deletion of thioredoxin-interacting protein regulates cardiac dysfunction in response to pressure overload.
6/2004	Thioredoxin-interacting protein controls cardiac hypertrophy through regulation of thioredoxin activity.

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Jun Yoshioka Research Topics

Disease

5	Hyperglycemia 01/2021 - 07/2004
4	Heart Failure 01/2019 - 12/2007
3	Myocardial Ischemia (Ischemic Heart Diseases) 01/2017 - 01/2012
3	Reperfusion Injury 01/2017 - 01/2012
2	Diabetic Cardiomyopathies 01/2021 - 01/2016
2	Infarction (Infarctions) 01/2017 - 01/2012
2	Insulin Resistance 06/2014 - 06/2010
2	Type 2 Diabetes Mellitus (MODY) 06/2014 - 06/2010
2	Cardiomegaly (Heart Hypertrophy) 12/2007 - 06/2004
1	Wounds and Injuries (Trauma) 01/2021
1	Frailty 01/2019
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2018
1	Hypoxia (Hypoxemia) 04/2015
1	Obesity 06/2014
1	Ischemia 02/2014
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2012
1	Ketosis 01/2008
1	Hyperlipidemias (Hyperlipidemia) 01/2008
1	Hypoglycemia (Reactive Hypoglycemia) 01/2008
1	Neoplasms (Cancer) 11/2006
1	Heart Diseases (Heart Disease) 11/2006
1	Hypertrophy 07/2005
1	Vascular Diseases (Vascular Disease) 07/2004
1	Diabetes Mellitus 07/2004
1	Cardiovascular Diseases (Cardiovascular Disease) 09/2003
1	Ventricular Remodeling 08/2003

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2021 - 06/2004
9	ThioredoxinsIBA 01/2021 - 06/2004
4	Glucose (Dextrose)FDA LinkGeneric 01/2017 - 06/2010
4	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2015 - 07/2004
2	DisulfidesIBA 01/2021 - 01/2008
2	AntioxidantsIBA 01/2021 - 06/2004
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 09/2003
2	Insulin (Novolin)FDA Link 01/2016 - 06/2010
1	Cysteine (L-Cysteine)FDA Link 01/2021
1	Phosphotransferases (Kinase)IBA 01/2018
1	InflammasomesIBA 01/2017
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2017
1	NLR ProteinsIBA 01/2017
1	Adrenergic Agents (Adrenergic Drugs)IBA 01/2016
1	Thioredoxin Reductase 2IBA 07/2015
1	Mechanistic Target of Rapamycin Complex 1IBA 04/2015
1	Adenosine Triphosphate (ATP)IBA 01/2012
1	Lactic Acid (Lactate)FDA LinkGeneric 01/2012
1	ArrestinIBA 06/2010
1	PPAR gammaIBA 06/2010
1	Oxidoreductases (Dehydrogenase)IBA 01/2008
1	(L)-Isomer Glucose (L-Glucose)IBA 12/2006
1	Heparin (Liquaemin)FDA LinkGeneric 07/2005
1	Heparin-binding EGF-like Growth Factor (HB-EGF)IBA 07/2005
1	Connexin 43 (Connexin43)IBA 07/2005
1	Epidermal Growth Factor (EGF)IBA 07/2005
1	p38 Mitogen-Activated Protein KinasesIBA 07/2004
1	CollagenIBA 08/2003

Therapy/Procedure

1	Ligation 01/2012
1	Therapeutics 01/2012